Self-Injurious Behavior: Gene–Brain–Behavior Relationships

Pages: 405
Item #: 431673A
ISBN: 978-1-55798-885-0
List Price: $19.95
Member/Affiliate Price: $19.95
Copyright: 2002
Format: Hardcover
Availability: In Stock
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Self-Injurious Behavior is a comprehensive, interdisciplinary review of the research on etiology and treatment of this chronic condition for which there is no known apparent cure. With an estimated prevalence rate of 13%, self-injurious behavior occurs most frequently among persons who are retarded and autistic. In this volume, the field's leading researchers examine a new generation of models and theories with a level of specificity far beyond what was heretofore imagined possible. From the burgeoning area of research on functional assessment and the behavioral and biological antecedents of self-injurious behavior, to the role of Lesch-Nyhan Syndrome and opioid peptides, the work of these foremost basic, applied, and behavioral researchers is sure to greatly enhance fellow researchers', teachers', and clinicians' understanding of this devastating condition.

Table of Contents



I. Overview of Self-Injurious Behavior

  1. Self-Injury: Knowing What We're Looking For
    —Travis Thompson and Mary Caruso
  2. Self-Injury and Comorbid Behaviors in Developmental, Neurological, Psychiatric, and Genetic Disorders
    —James W. Bodfish and Mark H. Lewis
  3. Epidemiology of Self-Injurious Behavior in Mental Retardation: A Review
    —Johannes Rojahn and Anna J. Esbensen

II. Environmental Mechanisms and Intervention Strategies

  1. Treatment: Current Standards of Care and Their Research Implications
    —Iser G. DeLeon, Vanessa Rodriguez-Catter, and Michael F. Cataldo
  2. Environmental Determinants of Self-Injurious Behavior
    —Brian A. Iwata, Eileen M. Roscoe, Jennifer R. Zarcone, and David M. Richman
  3. Functional Assessment and Self-Restraint
    —Rachel L. Freeman, Robert H. Horner, and Joe Reichle
  4. The Impact of Functional Assessment on the Treatment of Self-Injurious Behavior
    —Sung Woo Kahng, Brian A. Iwata, and Adam B. Lewin
  5. Evolution of Stereotypy Into Self-Injury
    —Craig H. Kennedy
  6. Incidence of Self-Injurious Behavior: Birth to 3 Years
    —Gershon Berkson and Megan Tupa
  7. Self-Injurious Behavior in Captive Macaque Monkeys
    —Melinda A. Novak, Carolyn M. Crockett, and Gene P. Sackett

III. Neurobiological Factors

  1. Dopaminergic Mechanisms in Self-Injurious Behavior and Related Disorders
    —Cortney A. Turner and Mark H. Lewis
  2. Pemoline and Other Dopaminergic Models of Self-Biting Behavior
    —Brian H. King
  3. Opioids and the Maintenance of Self-Injurious Behavior
    —Curt A. Sandman and Paul Touchette
  4. Sleep and Cyclical Variables Related to Self-Injurious and Other Destructive Behaviors
    —Wayne W. Fisher, Cathleen C. Piazza, and Henry S. Roane
  5. Self-Injury and Pain: Models and Mechanisms
    —Frank S. Symons
  6. Temporal and Force Dynamics of Self-Injury
    —Karl M. Newell and James W. Bodfish

IV. Lesch–Nyhan Syndrome as a Model Genetic Disorder of Self-Injurious Behavior

  1. Lessons From Lesch–Nyhan Syndrome
    —William L. Nyhan
  2. Neuroimaging Studies in Lesch–Nyhan Syndrome and Lesch–Nyhan Variants
    —James C. Harris, Dean F. Wong, Hyder A. Jinnah, D. Schretlen, and P. Barker
  3. Age-Dependent Reduction of Brain Dopamine: Relationship to Self-Injurious Behavior
    —George R. Breese
  4. A New Animal Model for Lesch–Nyhan Syndrome: Calcium Channel Activation With Bay K 8644
    —Suhail Kasim, Zubair Khan, and H.A. Jinnah
  5. Replacement Therapy for the Treatment of Lesch–Nyhan Syndrome
    —Richard E. Tessel, Pippa S. Loupe, and Stephen R. Schroeder


Author Index

Subject Index