Animal Research and Human Health: Advancing Human Welfare Through Behavioral Science demonstrates how the dynamic interplay between human and animal research has led to significant advances in diverse areas of psychology. Students are shown the value of this research by leading experts, who describe the paradigmatic use of laboratory animal models for studying and redressing such societal problems as anxiety, stress, aggression, depression, drug abuse, and dementia.
Chapters describe studies that have advanced understanding of the etiology and treatment of depression; behavioral techniques and medications to improve memory in patients with Alzheimer's disease or children with developmental disabilities; the importance of stress and nutrition in the development of hypertension; pharmacological, physical, and psychological interventions that relieve pain and suffering and allow paraplegic patients to walk with assistance; and one of the most effective treatments for cocaine and other drug addictions. This book will be an important resource for teachers and students of psychology at many levels, from introductory to advanced, who would like to explore how research with laboratory animals has enhanced and continues to enrich psychology.
Individual chapters of this book are available to purchase online.
- Basic Issues in the Use of Animals in Health Research
—J. Bruce Overmier and Marilyn E. Carroll
I. Anxiety, Stress, Aggression, and Depression
- Understanding, Treating, and Preventing Anxiety, Phobias, and Anxiety Disorders
—Richard E. Zinbarg and Susan Mineka
- Eating, Emotion, and the Organization of Behavior
—Nancy K. Dess
- Research on Animal Aggression: Emerging Successes for Understanding Determinants of Human Violence
—Klaus A. Miczek
- Learned Helplessness and Depression
—Vincent M. LoLordo
II. Drug Abuse
- Consequences of Early Exposure to Alcohol: How Animal Studies Reveal Later Patterns of Use and Abuse in Humans
—Norman E. Spear and Juan Carlos Molina
- Behavioral Pharmacology of Commonly Abused Drugs: Concordance Between Laboratory Studies Conducted With Animals and Humans
—Craig R. Rush, Nancy A. Ator, Cathy A. Simpson, and Warren K. Bickel
- Can Marijuana Use Lead to Marijuana Dependence?
—Alan J. Budney and Jenny Wiley
- Nicotine Self-Administration in Animals and Humans
—William A. Corrigall
- Nondrug Incentives to Treat Drug Abuse: Laboratory and Clinical Developments
—Marilyn E. Carroll, Warren K. Bickel, and Stephen T. Higgins
- Complementary Examination of Medications for Drug Abuse: Preclinical, Human Laboratory, and Clinical Research
III. Sleep, Illness, Injury, and Pain
- When Sleep Is Not Good for You
—Adrian R. Morrison
- Developmental Psychobiology of Hypertension: Contributions of Genetically Defined Animal Models
- Spinal Cord Injury: From Animal Research to Human Therapy
—James W. Grau and Robin L. Joynes
- Clinical Implications of Animal Pain Research
—Mary W. Meagher
IV. Learning, Memory, and Cognition
- Birds, Brains, and Visual Behavior: The Comparative Psychology of Perception
—Robert G. Cook and Jennifer Holtzinger
- Pick the Flowers and Mind Your A's and 2's! Categorization by Pigeons and Infants
—Edward A. Wasserman and Carolyn Rovee-Collier
- Using Animal Models to Address the Memory Deficits of Wernicke–Korsakoff Syndrome
—Angela K. Hochhalter, Whitney A. Sweeney, Lisa M. Savage, Bruce L. Bakke, and J. Bruce Overmier
- Drug Enhancement of Memory in Aged Rodents and Humans
—Paul E. Gold
- Effects of Estrogen on Cognition: Implications for Menopause
—Donna L. Korol and Carol A. Manning
- Insights About Learning in Alzheimer's Disease From the Animal Model
—Diana S. Woodruff-Pak
V. Conclusion: Reflections on Laboratory Animal Research
- A Scientist's Perspective on the Ethics of Using Animals in Behavioral Research
—Adrian R. Morrison
Appendix: Additional Reading
About the Editors
Marilyn E. Carroll, PhD, received her degree in psychobiology and neuroscience from Florida State University. She is currently a professor of psychiatry and an adjunct professor of psychology and neuroscience at the University of Minnesota, Minneapolis. She conducts basic research on the vulnerability to and treatment of drug abuse and has published over 140 research articles, reviews, books, and chapters. Her research has been supported by a MERIT award and other grants from the National Institute on Drug Abuse (NIDA).
Dr. Carroll has been president of Division 28 (Psychopharmacology and Substance Abuse) of the American Psychological Association (APA) and a member of the APA Committee on Animal Research Ethics. In August 2001, she received the APA Division 28 Brady-Schuster Award for her research in psychopharmacology and substance abuse. Dr. Carroll has also been president of the International Group of Scientists Investigating the Reinforcing Effects of Drugs (ISGIDAR). She has been a member of several NIDA review panels and is on the editorial board of the journals Experimental and Clinical Psychopharmacology, Psychopharmacology, and the Betty Ford Center Newsletter.
J. Bruce Overmier, PhD, is professor of psychology at the University of Minnesota, Minneapolis, and professor II of biological and medical psychology at the University of Bergen in Norway. Dr. Overmier's research spans specialties of learning, memory, stress, psychosomatic disorders, and their biological substrates. He has authored more than 170 refereed research articles, book chapters, and books with funding provided by the National Institute of Mental Health, the National Institute of Child Health and Human Development, the National Science Foundation, the Norwegian Research Council, and the University of Minnesota.
Dr. Overmier has sat on the Board of Directors of the American Psychological Society and the American Psychological Association (APA). He is past president of the APA's Division 6 (Behavioral Neuroscience and Comparative Psychology) and Division 3 (Experimental Psychology). Since 1994, he has served as associate editor for the American Psychologist. In 1990, Dr. Overmier received the honorary doctor of science degree from Kenyon College, and in 1999, he won the Quad-L Award in Psychology from the University of New Mexico.