Supplemental Materials

In this grid, the information on effect sizes incorporated from Figure 3 on p. 216 of Zou et al’s (2015) review is presented first across the top row followed by information for the Cipriani et al (2016). Each column in the grid reflects a particular treatment or treatment comparison from the reviews while each row reflects a particular outcome (i.e., reduction in depressive symptoms). The effect size along with relevant information (i.e., confidence interval) is presented at the intersection of rows and columns. This is followed by information on the panel’s ratings of the benefits, harms, balance of benefits vs. harms, patient values and preferences, applicability, and overall recommendation statement for each intervention or comparison of treatments.

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In this grid, the information for the Gartlehner et al. (2015) is presented first across the top row followed by the additional reviews, Cuijpers et al (2014), Driessen et al (2015), Cuijpers et al (2012), VA/DoD evidence synthesis report (ECRI Institute, 2015), and Cuijpers et al (2016). Each column in the grid reflects a particular treatment or treatment comparison from the reviews while each row reflects a particular outcome (i.e., reduction in depressive symptoms). The effect size along with relevant information (i.e., confidence interval) is presented at the intersection of rows and columns. This is followed by information on the panel’s ratings of the benefits, harms, balance of benefits vs harms, patient values and preferences, applicability, and overall recommendation statement for each intervention or comparison of treatments.

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This document provides additional information relating to the Clinical Practice Guideline for the Treatment of Depression.

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