The devastating psychological, physical, and spiritual damage wrought by the misuse of drugs is indisputable. However, there is a recurring debate over the causes of substance abuse that typically divides along two common assumptions: People either abuse drugs and alcohol out of sheer pleasure-seeking drives run amok or to escape or assuage aversive states of comorbid anxiety or depression.

Substance Abuse and Emotion goes beyond this dichotomy in its exploration of recent, significant field observations, theory construction and rigorous testing, and laboratory research to advance working models for a new research paradigm on substance abuse and comorbidity. Notably, the relationship between drugs and emotion is emerging as paramount in understanding drug abuse etiology, maintenance, and relapse.

Part I of this edited volume examines various theoretical perspectives on the interrelationship between substance abuse and emotion, such as craving and positive/negative reinforcement; cognitive theories; relapse; and developmental, sociobiological, and evolutionary perspectives.

Part II explores new assessment methodologies, such as "ecological momentary assessment" and the linkage between affect and cognitive deficits among drug users. The book concludes with a research agenda to expand the volume's new paradigm in understanding and treating substance abuse.

Table of Contents



Introduction: The Complex Interplay Between Substance Abuse and Emotion
—Jon D. Kassel and Jennifer C. Veilleux

I. Theoretical Perspectives

  1. Negative Reinforcement: Possible Clinical Implications of an Integrative Model
    —Danielle E. McCarthy, John J. Curtin, Megan E. Piper, and Timothy B. Baker
  2. Positive Reinforcement Theories of Drug Use
    —Harriet de Wit and Luan Phan
  3. Cognitive Theories of Drug Effects on Emotion
    —Jon D. Kassel, Margaret C. Wardle, Adrienne J. Heinz, and Justin E. Greenstein
  4. Drug Craving and Affect
    —Stephen T. Tiffany
  5. Developmental Perspectives: Affect and Adolescent Substance Use
    —Craig R. Colder, Laurie Chassin, Matthew R. Lee, and Ian K. Villalta
  6. Evolutionary Substrates of Addiction: The Neurochemistries of Pleasure Seeking and Social Bonding in the Mammalian Brain
    —Jaak Panksepp

II. Advances in Assessment, Methodology, and Treatment

  1. Emotions and Relapse in Substance Use: Evidence for a Complex Interaction Among Psychological, Social, and Biological Processes
    —Katie Witkiewitz and Johnny Wu
  2. The Complexities of Modeling Mood–Drinking Relationships: Lessons Learned From Daily Process Research
    —Cynthia Mohr, Stephen Armeli, Howard Tennen, and Michael Todd
  3. Ecological Momentary Assessment of Mood–Smoking Relationships in Adolescent Smokers
    —Robin Mermelstein, Donald Hedeker, and Sally Weinstein
  4. Cerebral Deficits Associated With Impaired Cognition and Regulation of Emotion in Methamphetamine Abuse
    —Andy C. Dean and Edythe D. London
  5. Addiction and Emotion: Theories, Assessment Techniques, and Treatment Implications
    —David H. Epstein, Jessica Wilner-Reid, and Kenzie L. Preston

Afterword: New Frontiers in Substance Abuse and Emotion
—Jon D. Kassel and Daniel P. Evatt


About the Editor

Editor Bio

Jon D. Kassel, PhD, graduated magna cum laude from the University of Minnesota in 1987 and received his doctorate from the University of Pittsburgh in 1995. He completed a clinical internship at Brown University, followed by his first academic appointment as an assistant professor of clinical and health psychology at the University Florida in 1995. Since 1998, he has been a faculty member in the Department of Psychology at the University of Illinois at Chicago, where he is a professor of psychology and director of the Substance Use Research Laboratory.

Dr. Kassel has received wide recognition for his research on substance abuse, including the Ferno Award for Innovative Research on Nicotine and Tobacco from the Society for Research on Nicotine and Tobacco in 2000, the Outstanding Early Career Contributions Award from the Special Interest Group on Addictive Behaviors of the Association for Cognitive and Behavior Therapies in 2000, the Glaxo Young Investigator Award from the Society of Behavioral Medicine in 2003, and the Distinguished Scientific Early Career Contributions Award from Division 50 (Addictions) of the American Psychological Association in 2004. His work has been funded by the National Institute on Alcohol Abuse and Alcoholism and the National Cancer Institute.

Dr. Kassel has authored more than 70 articles and chapters. He has served as a consulting editor for Psychology of Addictive Behaviors and the Journal of Consulting and Clinical Psychology. He is at present a standing member of the Risk, Prevention, and Intervention for Addictions Study Section of the National Institute of Health. Dr. Kassel's research is focused on delineating the processes that subserve drug effects, in particular, cigarette smoking and nicotine, on emotional response. This is his first edited volume.