Note: In 2025, the APA Board of Directors appointed a multidisciplinary panel to update the 2019 Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts. Reports on the panel’s progress and requests for input will be made periodically to the APA Council of Representatives, APA boards and committees, APA members, and the broader public.
The 2019 guideline recommends interventions for the treatment of depression in children and adolescents, adults, and older adults. Recommendations are based on a systematic review of the scientific evidence, a weighing of the benefits and harms of interventions, consideration of what is known about patient values and preferences, and consideration of the applicability of the evidence across demographic groups and settings.
See Placing Clinical Practice Guidelines in Context for guidance on use of this guideline.
