The 2025 guideline recommends interventions for the treatment of PTSD in adults. Recommendations are based on a systematic review of the scientific evidence, a weighing of the benefits and harms of interventions, consideration of what is known about patient values and preferences, and consideration of the applicability of the evidence across demographic groups and settings.

See Placing Clinical Practice Guidelines in Context for guidance on use of this guideline.
See ASC statement on the evidentiary bases of clinical practice guidelines acknowledging the state of psychotherapy science.

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Placing Clinical Practice Guidelines in Context

Provision of high quality, effective care that reduces symptoms and helps the patient return to higher levels of functioning is a shared goal for patients and their families, practitioners, policy makers, and administrators. But knowing which information to trust and prioritize is not easy, and synthesizing available research and determining preferable care options can be daunting. Clinical practice guidelines are an essential tool to guide clinical decision-making and make it easier for patients to get the care they need. Clinical practice guidelines are intended to be a central—but clearly not the only—determinant of treatment choice. Other factors include patients’ preferences and histories, providers’ expertise and judgment, nonspecific factors in psychotherapy, and patients’ individual differences.

Advisory Steering Committee Statement on the Evidentiary Bases of Clinical Practice Guidelines

A mission of the Advisory Steering Committee for development of clinical practice guidelines is to guide the field in its efforts to continue developing and disseminating evidence about psychotherapy and other interventions. Clinical practice guidelines represent the state of the literature and leading recommendations to guide high-quality clinical care. This statement is intended to encourage attention toward current evidence while acknowledging the state of psychotherapy science and inherent limitations of our current processes and evidentiary base.

For Patients and Families

More resources are available in the Patients and Families section.

Resources for the Treatment of PTSD in Children and Adolescents

For more information on treating children and adolescents with PTSD, please refer to the following resources:

Last updated: April 2025Date created: 2017