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Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts
The guideline recommends interventions for the treatment of depression in children and adolescents, adults, and older adults. Recommendations are based on a systematic review of the scientific evidence, a weighing of the benefits and harms of interventions, consideration of what is known about patient values and preferences, and consideration of the applicability of the evidence across demographic groups and settings.
Depression guideline update panel
A multidisciplinary panel updated the 2019 Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts
Resources for clinicians for the treatment of depression
Find links to treatment manuals, continuing education and other courses, training and professional organizations, case examples, and more.
Depression Assessment Instruments
Initial assessments of depressive symptoms can help determine possible treatment options, and periodic assessment throughout care can guide treatment and gauge progress.
Depression Treatments for Older Adults
A variety of informational articles about group cognitive-behavioral therapy, interpersonal psychotherapy, group life-review/reminiscence therapy and medications for depression.
Depression Treatments for Children and Adolescents
A variety of informational articles about cognitive-behavioral therapy, interpersonal psychotherapy for adolescents and medications for depression.
Patients and Families — Understanding the Guideline for Treatment of Depression
A variety of informational articles about depression, getting help, psychotherapies, medications and barriers to treatment.
Case Examples
Examples of recommended interventions in the treatment of depression across the lifespan, including interpersonal psychotherapy for adults, behavioral therapy and cognitive therapy.
Resources for Clinicians for the Treatment of Depression in Older Adults
Resources from manuals, webinars, case examples, books and videos, podcast and national organizations for the treatment of depression in older adults.
Resources for Clinicians for the Treatment of Depression in Adults
Resources from manuals, webinars, case examples, books and videos, podcast and national organizations for the treatment of depression in adults.
Resources for Clinicians for the Treatment of Depression in Children & Adolescents
Resources from manuals, webinars, case examples, books and videos, podcast and national organizations for the treatment of depression in children and adolescents.
Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts [PDF]
Recommendations for the treatment of depressive disorders (including major depression, subsyndromal depression, and persistent depressive disorder). This guideline addresses three developmental cohorts: children and adolescents; general adults; and older adults (ages 60 and over).
Older Adults and Depression [PDF]
National Institute of Mental Health brochure describing signs of depression in older adults and where to find treatment.
Depression Treatments
Treatments of depression based on age, divided into children/teens, adults and older adults.
Depression Treatments for Adults
APA's Clinical Practice Guideline recommends seven psychotherapy interventions as well as a second-generation antidepressant (selective serotonin reuptake inhibitors—SSRIs—serotonin-norepinephrine reuptake inhibitors—SNRIs—or norepinephrine/dopamine reuptake inhibitors—NDRIs) for the treatment of depression in adults.
Responses to Public Comments on Draft Version of the APA Clinical Practice Guideline for the Treatment of Depression [PDF]
Approximately 120 individuals or groups submitted comments during the public comment period, August 23 to October 25, 2018.
Reminiscence Functions Scale [PDF]
The RFS assesses the frequency with which adults, 18 years and older, engage in the act of recollecting past experiences or events.
Patient Health Questionnaire-9 (PHQ-9) [PDF]
The Patient Health Questionnaire (PHQ) is a self-report measure designed to screen depressive symptoms, including feeling hopeless, sleep issues, appetite and concentration.
Children’s Depression Inventory 2nd Edition™ [PDF]
The CDI 2 can be used in both educational and clinical settings to evaluate depressive symptoms in children and adolescents.
Montgomery and Åsberg (MADRS) Depression Rating Scale [PDF]
The 10-item Montgomery-Åsberg Depression Rating Scale (MADRS) measures severity of depression in individuals 18 years and older.
Hamilton Depression Rating Scale (HAM-D) [PDF]
The HAM-D is designed to rate the severity of depression in patients, measuring things such as mood, insomnia, guilt, agitation, anxiety, appetite.
Center for Epidemiologic Studies Depression Scale (CES-D), NIMH [PDF]
The scale can be used for children as young as 6 and through older adulthood measure major dimensions of depression experienced in the past week. Measures include appetite, feelings of hopefulness or failure, loneliness, sadness, or crying.
Child Behavior Checklist (CBCL) [PDF]
The Achenbach System of Empirically Based Assessment is used to detect behavioral and emotional problems in children and adolescents. It includes anxiety, depression, physical complaints, problems with thinking or attention, and rule-breaking or aggressive behavior.
Supplemental Materials
Information about the psychotherapies for depression in children and adolescents, treatment of young and middle aged adult depression, and the appendices to the guideline.
Appendices to the APA Guideline for the Treatment of Depression [PDF]
Decision tables, definitions of key terms, conflict of interest forms, and dose, timing and session duration of treatments.