Managing Clinical Heterogeneity in Psychopathology:

View the table of contents with abstracts on APA PsycNet

Introduction

• Managing Clinical Heterogeneity in Psychopathology: Perspectives From Brain Research
  Katherine S. F. Damme and Vijay A. Mittal

Commentaries

• Of Strong Swords and Fine Scalpels: Developing Robust Clinical Principles to Cut Through Heterogeneity
  Peter F. Hitchcock
• From Deconstruction to Reconstruction: A Search for Natural Kinds in Developmental Psychopathology
  Melissa A. Brotman, Simone P. Haller, Daniel S. Pine, and Nathan A. Fox
• Shared Principles for Disentangling Heterogeneity in Neuroscience and Psychopathology
  Brian Kraus and Caterina Gratton

Special Issue Articles

• Two-Year Trajectories of Anhedonia in Adolescents at Transdiagnostic Risk for Severe Mental Illness: Association With Clinical Symptoms and Brain-Symptom Links
  Tina Gupta, T. H. Stanley Seah, Kristen L. Eckstrand, Manivel Rengasamy, Chloe Horter, Jennifer Silk, Neil Jones, Neal D. Ryan, Mary L. Phillips, Gretchen Haas, Melissa Nance, Morgan Lindenmuth,and Erika E. Forbes
• Prospective Associations Between Early Adolescent Reward Functioning and Later Dimensions of Psychopathology
  Matthew Mattoni, Samantha Pegg, Autumn Kujawa, Daniel N. Klein, and Thomas M. Olino
• Heart Rate Variability as a Biomarker for Transdiagnostic Depressive and Anxiety Symptom Trajectory in Adolescents and Young Adults
  Alainna Wen, Tomislav D. Zbozinek, Julian Ruiz, Richard E. Zinbarg, Robin Nusslock, and Michelle G. Craske
• Using Machine Learning to Derive Neurobiological Subtypes of General Psychopathology in Late Childhood
  Gabrielle E. Reimann, Randolph M. Dupont, Aristeidis Sotiras, Tom Earnest, Hee Jung Jeong, E. Leighton Durham, Camille Archer, Tyler M. Moore, Benjamin B. Lahey, and Antonia N. Kaczkurkin
• Leveraging Normative Personality Data and Machine Learning to Examine the Brain Structure Correlates of Obsessive-Compulsive Personality Disorder Traits
  Allison L. Moreau, Aaron J. Gorelik, Annchen Knodt, Deanna M. Barch, Ahmad R. Hariri, Douglas B. Samuel, Thomas F. Oltmanns, Alexander S. Hatoum, and Ryan Bogdan
• Toward Understanding Autism Heterogeneity: Identifying Clinical Subgroups and Neuroanatomical Deviations
  Jente Meijer, Bruno Hebling Vieira, Camille Elleaume, Zofia Baranczuk-Turska, Nicolas Langer, and Dorothea L. Floris
• Making the Most of Errors: Utilizing Erroneous Classifications Generated by Machine-Learning Models of Neuroimaging Data to Capture Disorder Heterogeneity
  Sarah M. Olshan, Corey J. Richier, Kyle A. Baacke, Gregory A. Miller, and Wendy Heller
• Three Principles for the Utility of Simple Tasks That Assess Elemental Processes in Parsing Heterogeneity
  Alexandra B. Moussa-Tooks, Deanna M. Barch, and William P. Hetrick
• The Hierarchical Taxonomy of Psychopathology and the Search for Neurobiological Substrates of Mental Illness: A Systematic Review and Roadmap for Future Research
  Colin G. DeYoung, Scott D. Blain, Robert D. Latzman, Rachael G. Grazioplene, John D. Haltigan, Roman Kotov, Giorgia Michelini, Noah C. Venables, Anna R. Docherty, Vina M. Goghari, Alexander M. Kallen, Elizabeth A. Martin, Isabella M. Palumbo, Christopher J. Patrick, Emily R. Perkins, Alexander J. Shackman, Madeline E. Snyder, Kaitlyn E. Tobin, and the HiTOP Neurobiological Foundations Workgroup
• Integrating Threat Conditioning and the Hierarchical Taxonomy of Psychopathology to Advance the Study of Anxiety-Related Psychopathology
  Samuel E. Cooper, Emily R. Perkins, Ryan D. Webler, Joseph E. Dunsmoor, and Robert F. Krueger
• Clarifying the Place of P300 in the Empirical Structure of Psychopathology Over Development Emily R. Perkins, Jeremy Harper, Jonathan D. Schaefer, Stephen M. Malone, William G. Iacono, Sylia Wilson, and Christopher J. Patrick