This issue presents 6 original research reports describing the use of mice and rats to model neurodevelopmental disorders, depressive disorders, anxiety disorders, and substance use disorders.
Collectively, these studies demonstrate the progress of the field and the gaps and challenges that remain. They also illustrate the range of conditions that are informed by animal models and identify the clinical populations that stand to benefit from their use in preclinical research.
Guest Editor
Table of contents
- Introduction to Special Issue on Animal Models of Neuropsychiatric Disorders and Substance Use Disorders: Progress and Gaps
Pages 61–63
Smith, Mark A.; Evans, Suzette M. - Effects of Adolescent Exposure to Methylmercury and d-Amphetamine on Reversal Learning and an Extradimensional Shift in Male Mice
Pages 64–73
Boomhower, Steven R.; Newland, M. Christopher - Adolescent Chronic Restraint Stress (aCRS) Elicits Robust Depressive-Like Behavior in Freely Cycling, Adult Female Rats Without Increasing Anxiety-Like Behaviors
Pages 74–83
Hibicke, Meghan; Graham, Martha A.; Hayslett, Renée L. - Differential Characteristics of Ketamine Self-Administration in the Olfactory Bulbectomy Model of Depression in Male Rats
Pages 84–93
Babinska, Zuzana; Ruda-Kucerova, Jana - Chronic Corticosterone Administration Effects on Behavioral Emotionality in Female C57BL6 Mice
Pages 94–104
Mekiri, Maryam; Gardier, Alain M.; David, Denis J.; Guilloux, Jean-Philippe - Topiramate Reduces Basal Anxiety and Relieves Ethanol Withdrawal-Induced Anxious Behaviors in Male Rats
Pages 105–113
Junqueira-Ayres, Décio D.; Asth, Laila; Ayres, Adriana S. F. S. J.; Lobão-Soares, Bruno; Soares-Rachetti, Vanessa de Paula; Gavioli, Elaine C. - Cocaine Self-Administration in Male and Female Rats Perinatally Exposed to PCBs: Evaluating Drug Use in an Animal Model of Environmental Contaminant Exposure
Pages 114–124
Miller, Mellessa M.; Meyer, Abby E.; Sprowles, Jenna L. N.; Sable, Helen J. K.
